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The following definitions are used frequency: very common (occurring in more than 10% of patients), common (occurs between 1 and 10% of patients), rare (occurs between 0.1 and 1% of patients), rare (occurs 0.01 to 0.1% of patients) and very rare (occurs in less than 0.01% of the patients).

blood and lymphatic system disorders

- very rare reactions: hemolytic anemia (anemia due to abnormal breakdown of erythrocytes in blood vessels), aplastic anemia (decreased production of red blood cells) and thrombocytopenia (reduced platelet count).

heart disorders

- Common reactions bradycardia (decreased number of heartbeats) generally moderate and dose-dependent;

- unusual reactions: onset or worsening of arrhythmia (heart rhythm disorders), then sometimes from cardiac arrest; driving changes (sino-atrial block and atrioventricular various degrees);

- very rare reactions: marked bradycardia and sinus arrest in patients with sinus node dysfunction and / or in elderly patients;

- Reactions with unknown frequency: Torsade de Pointes (severe type of change in heartbeat).

endocrine disorders (glandular)

- common reactions: hypothyroidism (decreased thyroid gland function); hyperthyroidism (thyroid gland increasing function), sometimes fatal.

- very rare reactions: syndrome of inappropriate secretion of antidiuretic hormone (SIADH)

eye disorders

- very common reactions: microdeposits on the cornea (clear part of the eye that is in front of the iris, which is the "eye color"), usually limited to subpupilar area. They may be associated with the perception of colored halos, in bright light or blurred vision. The corneal microdeposits consist of complex lipid deposits and are reversible some time after cessation of treatment.

- very rare reactions: optic neuropathy / neuritis (nerve disease / degenerative or inflammatory lesion of nerves), which can progress to blindness (see warnings).

gastrointestinal (digestive)

- very common reactions: benign gastrointestinal disorders (nausea, vomiting, foul taste for healthy foods) may occur due to the loading dose and disappear with dose reduction.

general disorders

- Reaction of unknown frequency: Granuloma (small inflammatory nodules), including bone marrow granuloma.

Hepato-biliary disorders (liver and bile)

- very common reactions: Isolated increase in serum transaminases (liver enzymes) which are usually moderate (1.5 to 3 times normal) at the start of therapy. Levels may return to normal with dose reduction or even spontaneously;

- common reactions: acute liver disorders with elevated serum and / or jaundice transaminases (yellowing of the skin), including liver failure, which can sometimes be fatal;

- very rare reactions: chronic liver disease (pseudo alcoholic hepatitis, cirrhosis), sometimes fatal.

Immune system disorders

- Not known: angioneurotic edema - Quincke edema (non-inflammatory swelling of the skin, mucous membranes, viscera and brain of sudden onset and lasting from hours to days, accompanied by other symptoms such as fever).

Investigation

- very rare reaction: increase in serum creatinine level.

nervous system disorders

- common reactions: extrapyramidal tremor, nightmares and sleep disorders;

- unusual reactions: sensorimotor peripheral neuropathy (disorder of the peripheral nerves) and / or myopathy are usually reversible upon discontinuation of treatment;

- very rare reactions: Cerebellar ataxia (lack of control over the muscles), benign intracranial hypertension (characterized by headache, nausea, papilledema, peripheral constriction of visual fields, transient visual obscurations, and pulsatile tinnitus), headache (headache).

reproductive system disorders

- very rare reactions: epididymitis (epididymis inflammation of a testicle structure), impotence.

Respiratory, thoracic and mediastinal disorders

- common reactions: pulmonary toxicity (alveolar / interstitial pneumonitis or fibrosis, pleuritis, bronchiolitis obliterans organizing pneumonia) sometimes fatal;

- known: pulmonary hemorrhage.

- very rare reactions: bronchospasm (inflammation of the bronchi) in patients with severe respiratory failure, especially in asthmatic patients. respiratory distress syndrome, adult (type of lung failure), sometimes fatal, usually in the immediate post surgical period (see Warning and Interactions)

Skin and subcutaneous tissue disorders

- very common reaction: photosensitivity (light sensitivity);

- Common reactions: grayish pigment (gray color) or bluish skin in prolonged use or high daily doses. With cessation of treatment that slowly fades pigmentation;

- Reactions very rare erythema during the use of radiotherapy, "rash" skin, usually non-specific, exfoliative dermatitis, alopecia (hair loss).

- Not known: urticaria.

vascular disorders

very rare reaction: vasculitis (blood vessel inflammation).

Inform your doctor or pharmacist any undesirable effects related to the drug.

Also tell the company through its service.

over Ancoron

  • Full package insert Ancoron
  • What is Ancoron
  • Contraindications and risk Ancoron
  • Interactions of Ancoron
  • Ancoron use in pregnancy and breastfeeding
  • Dosage, dosage and usage instructions Ancoron
  • Adverse reactions Ancoron
  • Overdose Ancoron
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